Relevante Publikationen

sortiert nach der Thematik

DCM

  • Schultheiss HP, Fairweather D, Caforio ALP, Escher F, Hershberger RE, Lipshultz SE, Liu PP, Matsumori A, Mazzanti A, McMurray J, Priori SG. Dilated cardiomyopathy. Nat Rev Dis Primers. 2019 May 9;5(1):32. doi: 10.1038/s41572-019-0084-1. PMID: 31073128; PMCID: PMC7096917.
  • Ostermann K, Schultheiss HP, Noutsias M. Neural cell adhesion molecule expression in dilated cardiomyopathy is associated with intramyocardial inflammation and hypertrophy. Int J Cardiol. 2017 Aug 15;241:322-325. doi: 10.1016/j.ijcard.2017.03.072. Epub 2017 Mar 18. PMID: 28343767.
  • Spillmann F, Kühl U, Van Linthout S, Dominguez F, Escher F, Schultheiss HP, Pieske B, Tschöpe C. Reversible transition from a hypertrophic to a dilated cardiomyopathy. ESC Heart Fail. 2016 Jun;3(2):138-142. doi: 10.1002/ehf2.12072. Epub 2015 Dec 9. PMID: 27774273; PMCID: PMC5064744.
  • Savvatis K, Schultheiss HP, Tschöpe C. Endomyocardial biopsy and ultrastructural changes in dilated cardiomyopathy: taking a 'deeper' look into patients' prognosis. Eur Heart J. 2015 Mar 21;36(12):708-10. doi: 10.1093/eurheartj/ehu461. Epub 2014 Nov 28. PMID: 25433023.
  • Schultheiss HP, Noutsias M, Kühl U, Lassner D, Gross U, Poller W, Pauschinger M. Kardiomyopathien. Teil I: Klassifikation der Kardiomyopathien -- dilatative Kardiomyopathie [Cardiomyopathies. I: classification of cardiomyopathies--dilated cardiomyopathy]. Internist (Berl). 2005 Nov;46(11):1245-56; quiz 1257. German. doi: 10.1007/s00108-005-1483-9. PMID: 16228156.

Myocarditis

  • Escher F, Lassner D, Kühl U, Gross U, Westermann D, Poller W, Skurk C, Weitmann K, Hoffmann W, Tschöpe C, Schultheiss HP. Analysis of endomyocardial biopsies in suspected myocarditis--diagnostic value of left versus right ventricular biopsy. Int J Cardiol. 2014 Nov 15;177(1):76-8. doi: 10.1016/j.ijcard.2014.09.071. Epub 2014 Sep 28. PMID: 25499345.
  • Escher F, Tschöepe C, Lassner D, Schultheiss HP. Myocarditis and inflammatory cardiomyopathy: from diagnosis to treatment. Turk Kardiyol Dern Ars. 2015 Dec;43(8):739-48. doi: 10.5543/tkda.2015.47750. PMID: 26717340.
  • Schmidt-Lucke C, Escher F, Van Linthout S, Kühl U, Miteva K, Ringe J, Zobel T, Schultheiss HP, Tschöpe C. Cardiac migration of endogenous mesenchymal stromal cells in patients with inflammatory cardiomyopathy. Mediators Inflamm. 2015;2015:308185. doi: 10.1155/2015/308185. Epub 2015 Feb 28. PMID: 25814787; PMCID: PMC4359807.
  • Escher F, Kühl U, Lassner D, Stroux A, Westermann D, Skurk C, Tschöpe C,Poller W, Schultheiss HP. Presence of perforin in endomyocardial biopsies of patients with inflammatory cardiomyopathy predicts poor outcome. Eur J Heart Fail. 2014 Oct;16(10):1066-72. doi: 10.1002/ejhf.148. Epub 2014 Aug 28. PMID: 25163698.
  • Savvatis K, Müller I, Fröhlich M, Pappritz K, Zietsch C, Hamdani N, Grote K, Schieffer B, Klingel K, Van Linthout S, Linke WA, Schultheiss HP, Tschöpe C. Interleukin-6 receptor inhibition modulates the immune reaction and restores titin phosphorylation in experimental myocarditis. Basic Res Cardiol. 2014;109(6):449. doi: 10.1007/s00395-014-0449-2. Epub 2014 Oct 25. PMID: 25344085.
  • Caforio AL, Pankuweit S, Arbustini E, Basso C, Gimeno-Blanes J, Felix SB, Fu M, Heliö T, Heymans S, Jahns R, Klingel K, Linhart A, Maisch B, McKenna W, Mogensen J, Pinto YM, Ristic A, Schultheiss HP, Seggewiss H, Tavazzi L, Thiene G, Yilmaz A, Charron P, Elliott PM; European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J. 2013 Sep;34(33):2636-48, 2648a-2648d. doi: 10.1093/eurheartj/eht210. Epub 2013 Jul 3. PMID: 23824828.
  • Kasner M, Sinning D, Escher F, Lassner D, Kühl U, Schultheiss HP, Tschöpe C. The utility of speckle tracking imaging in the diagnostic of acute myocarditis, as proven by endomyocardial biopsy. Int J Cardiol. 2013 Oct 3;168(3):3023-4. doi: 10.1016/j.ijcard.2013.04.016. Epub 2013 May 20. PMID: 23701925.
  • Skurk C, Schultheiss HP. Mononuclear cell secretome in autoimmune myocarditis. Eur Heart J. 2015 Mar 14;36(11):650-2. doi: 1093/eurheartj/eht050. Epub 2013 Mar 19. PMID: 23513211.
  • Schultheiss HP. Die genetische Testung ist der Myokardbiopsie bei Kardiomyopathien überlegen - contra [Genetic testing is superior to biopsy of the myocardium in cardiomyopathy - no]. Dtsch Med Wochenschr. 2013 Mar;138(12):599. German. doi: 10.1055/s-0032-1332904. Epub 2013 Mar 12. PMID: 23483422.
  • Escher F, Kasner M, Kühl U, Heymer J, Wilkenshoff U, Tschöpe C, Schultheiss HP. New echocardiographic findings correlate with intramyocardial inflammation in endomyocardial biopsies of patients with acute myocarditis and inflammatory cardiomyopathy. Mediators Inflamm. 2013;2013:875420. doi: 10.1155/2013/875420. Epub 2013 Mar 20. PMID: 23576857; PMCID: PMC3616345.
  • Kühl U, Schultheiss HP. Myocarditis: early biopsy allows for tailored regenerative treatment. Dtsch Arztebl Int. 2012 May;109(20):361-8. doi: 10.3238/arztebl.2012.0361. Epub 2012 May 18. PMID: 22685492; PMCID: PMC3370379.
  • Schultheiss HP, Kühl U. Why is diagnosis of infectious myocarditis such a challenge? Expert Rev Anti Infect Ther. 2011 Dec;9(12):1093-5. doi: 1586/eri.11.135. PMID: 22114957.
  • Schultheiss HP, Kühl U, Cooper LT. The management of myocarditis. Eur Heart J. 2011 Nov;32(21):2616-25. doi: 10.1093/eurheartj/ehr165. Epub 2011 Jun 23. PMID: 21705357.
  • Escher F, Vetter R, Kühl U, Westermann D, Schultheiss HP, Tschöpe C. Fractalkine in human inflammatory cardiomyopathy. Heart. 2011 May;97(9):733-9. doi: 10.1136/hrt.2010.205716. Epub 2011 Feb 25. PMID: 21357373.
  • Escher F, Westermann D, Gaub R, Pronk J, Bock T, Al-Saadi N, Kühl U, Schultheiss HP, Tschöpe C. Development of diastolic heart failure in a 6-year follow-up study in patients after acute myocarditis. Heart. 2011 May;97(9):709-14. doi: 10.1136/hrt.2010.199489. Epub 2010 Dec 5. PMID: 21134904.
  • Kühl U, Schultheiss HP. Myocarditis in children. Heart Fail Clin. 2010 Oct;6(4):483-96, viii-ix. doi: 10.1016/j.hfc.2010.05.009. PMID: 20869648.
  • Schultheiss HP, Kühl U. Myokardbiopsie bei Kardiomyopathie: Wann und warum? [Endomyocardial biopsy in cardiomyopathy: when and why?]. Dtsch Med Wochenschr. 2009 Apr;134(15):769-72. German. doi: 10.1055/s-0029-1220229. Epub 2009 Apr 1. PMID: 19340757.
  • Schultheiss HP, Kühl U. Myokarditis [Myocarditis]. Dtsch Med Wochenschr. 2008 Dec;133 Suppl 8:S290-4. doi: 10.1055/s-0028-1100964. Epub 2008 Dec 15. PMID: 19085809.
  • Schultheiss HP, Kühl U. Stand der Diagnostik und Therapie der inflammatorischen Kardiomyopathie [State of diagnostics and therapy of inflammatory cardiomyopathie]. Internist (Berl). 2008 Jan;49(1):7-16. doi: 10.1007/s00108-007-1966-y. PMID: 18210028.
  • Strauer BE, Schultheiss HP. Entzündliche Herzerkrankungen [Inflammatory diseases of the heart]. Internist (Berl). 2008 Jan;49(1):5-6. German. doi: 10.1007/s00108-007-2004-9. PMID: 18210014.
  • Schultheiss HP. Im Fokus: inflammatorische Kardiomyopathie [In focus: Inflammatory cardiomyopathy]. Internist (Berl). 2006 Sep;47(9):970, 972-3. German. PMID: 17245840.
  • Schultheiss HP, Noutsias M, Kühl U, Gross U, Lassner D, Poller W, Pauschinger M. Kardiomyopathien Teil II: Hypertrophe Kardiomyopathie, restriktive Kardiomyopathie, arrhythmogene rechtsventrikuläre Kardiomyopathie [Cardiomyopathies II. Hypertrophic cardiomyopathy, restrictive cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy]. Internist (Berl). 2005 Dec;46(12):1373-85, quiz 1386-7. German. doi: 10.1007/s00108-005-1492-8. PMID: 16237514.

Heart Failure

  • Emrich T, Hahn F, Fleischmann D, Halfmann MC, Düber C, Varga-Szemes A, Escher F, Pefani E, Münzel T, Schultheiss HP, Kreitner KF, Wenzel P. T1 and T2 mapping to detect chronic inflammation in cardiac magnetic resonance imaging in heart failure with reduced ejection fraction. ESC Heart Fail. 2020 Aug 13;7(5):2544–52. doi: 10.1002/ehf2.12830. Epub ahead of print. PMID: 32790159; PMCID: PMC7524213.
  • Sotiriou E, Heiner S, Jansen T, Brandt M, Schmidt KH, Kreitner KF, Emrich T, Schultheiss HP, Schulz E, Münzel T, Wenzel P. Therapeutic implications of a combined diagnostic workup including endomyocardial biopsy in an all-comer population of patients with heart failure: a retrospective analysis. ESC Heart Fail. 2018 Aug;5(4):630-641. doi: 10.1002/ehf2.12296. Epub 2018 May 10. PMID: 29745463; PMCID: PMC6073026.
  • Lindner D, Zietsch C, Tank J, Sossalla S, Fluschnik N, Hinrichs S, Maier L, Poller W, Blankenberg S, Schultheiss HP, Tschöpe C, Westermann D. Cardiac fibroblasts support cardiac inflammation in heart failure. Basic Res Cardiol. 2014;109(5):428. doi: 10.1007/s00395-014-0428-7. Epub 2014 Aug 3. PMID: 25086637.

Virale Myokarditis

  • Schmidt-Lucke C, Zobel T, Escher F, Tschöpe C, Lassner D, Kühl U, Gubbe K, Volk HD, Schultheiss HP. Human Parvovirus B19 (B19V) Up-regulates CXCR4 Surface Expression of Circulating Angiogenic Cells: Implications for Cardiac Ischemia in B19V Cardiomyopathy. J Infect Dis. 2018 Jan 17;217(3):456-465. doi: 1093/infdis/jix309. PMID: 28961998.
  • Schmidt-Lucke C, Zobel T, Schrepfer S, Kuhl U, Wang D, Klingel K, Becher PM, Fechner H, Pozzuto T, Van Linthout S, Lassner D, Spillmann F, Escher F, Holinski S, Volk HD, Schultheiss HP, Tschope C. Impaired Endothelial Regeneration Through Human Parvovirus B19-Infected Circulating Angiogenic Cells in Patients With Cardiomyopathy. J Infect Dis. 2015 Oct 1;212(7):1070-81. doi: 10.1093/infdis/jiv178. Epub 2015 Mar 24. PMID: 25805750.
  • Escher F, Kühl U, Gross U, Westermann D, Poller W, Tschöpe C, Lassner D, Schultheiss HP. Aggravation of left ventricular dysfunction in patients with biopsy-proven cardiac human herpesvirus A and B infection. J Clin Virol. 2015 Feb;63:1-5. doi: 10.1016/j.jcv.2014.11.026. Epub 2014 Nov 29. PMID: 25600595.
  • Kühl U, Lassner D, Wallaschek N, Gross UM, Krueger GR, Seeberg B, Kaufer BB, Escher F, Poller W, Schultheiss HP. Chromosomally integrated human herpesvirus 6 in heart failure: prevalence and treatment. Eur J Heart Fail. 2015 Jan;17(1):9-19. doi: 10.1002/ejhf.194. Epub 2014 Nov 11. PMID: 25388833.
  • Kühl U, Schultheiss HP. Viral myocarditis. Swiss Med Wkly. 2014 Oct 2;144:w14010. doi: 10.4414/smw.2014.14010. PMID: 25275335.
  • Van Linthout S, Tschöpe C, Schultheiss HP. Lack in treatment options for virus-induced inflammatory cardiomyopathy: can iPS-derived cardiomyocytes close the gap? Circ Res. 2014 Aug 29;115(6):540-1. doi: 10.1161/CIRCRESAHA.114.304951. PMID: 25170089.
  • Kühl U, Ebermann L, Lassner D, Klingel K, Klumpe I, Winter J, Zeichhardt H, Schultheiss HP, Dörner A. Adenine nucleotide translocase 1 expression affects enterovirus infection in human and murine hearts. Int J Cardiol. 2014 Apr 1;172(3):e449-52. doi: 10.1016/j.ijcard.2013.12.315. Epub 2014 Jan 21. PMID: 24485628.
  • Kuhl U, Lassner D, Dorner A, Rohde M, Escher F, Seeberg B, Hertel E, Tschope C, Skurk C, Gross UM, Schultheiss HP, Poller W. A distinct subgroup of cardiomyopathy patients characterized by transcriptionally active cardiotropic erythrovirus and altered cardiac gene expression. Basic Res Cardiol. 2013 Sep;108(5):372. doi: 10.1007/s00395-013-0372-y. Epub 2013 Aug 11. Erratum in: Basic Res Cardiol. 2014 Jan;109(1):394. PMID: 23934091.
  • Kühl U, Schultheiss HP. Viral myocarditis: diagnosis, aetiology and management. Drugs. 2009 Jul 9;69(10):1287-302. doi: 10.2165/00003495-200969100-00001. PMID: 19583449.
  • Escher F, Modrow S, Sabi T, Kühl U, Lassner D, Schultheiss HP, Noutsias M. Parvovirus B19 profiles in patients presenting with acute myocarditis and chronic dilated cardiomyopathy. Med Sci Monit. 2008 Dec;14(12):CR589-97. PMID: 19043365.
  • Kühl U, Lassner D, Pauschinger M, Gross UM, Seeberg B, Noutsias M, Poller W, Schultheiss HP. Prevalence of erythrovirus genotypes in the myocardium of patients with dilated cardiomyopathy. J Med Virol. 2008 Jul;80(7):1243-51. doi: 10.1002/jmv.21187. PMID: 18461615.
  • Escher F, Kuhl U, Sabi T, Suckau L, Lassner D, Poller W, Schultheiss HP, Noutsias M. Immunohistological detection of Parvovirus B19 capsid proteins in endomyocardial biopsies from dilated cardiomyopathy patients. Med Sci Monit. 2008 Jun;14(6):CR333-338. PMID: 18509278.
  • Kühl U, Pauschinger M, Poller W, Schultheiss HP. Anti-viral treatment in patients with virus-induced cardiomyopathy. Ernst Schering Res Found Workshop. 2006;(55):323-42. doi: 10.1007/3-540-30822-9_18. PMID: 16329670.
  • Poller W, Fechner H, Kühl U, Pauschinger M, Schultheiss HP. New therapeutics targets in chronic viral cardiomyopathy. Ernst Schering Res Found Workshop. 2006;55(55):287-303. doi: 10.1007/3-540-30822-9_16. PMID: 16329668; PMCID: PMC7123174.
  • Schultheiss HP, Kühl U. Overview on chronic viral cardiomyopathy/chronic myocarditis. Ernst Schering Res Found Workshop. 2006;(55):3-18. doi: 10.1007/3-540-30822-9_1. PMID: 16329654.
  • Kühl U, Pauschinger M, Seeberg B, Lassner D, Noutsias M, Poller W, Schultheiss HP. Viral persistence in the myocardium is associated with progressive cardiac dysfunction. Circulation. 2005 Sep 27;112(13):1965-70. doi: 1161/CIRCULATIONAHA.105.548156. Epub 2005 Sep 19. PMID: 16172268.
  • Kühl U, Pauschinger M, Noutsias M, Seeberg B, Bock T, Lassner D, Poller W, Kandolf R, Schultheiss HP. High prevalence of viral genomes and multiple viral infections in the myocardium of adults with "idiopathic" left ventricular dysfunction. Circulation. 2005 Feb 22;111(7):887-93. doi: 10.1161/01.CIR.0000155616.07901.35. Epub 2005 Feb 7. PMID: 15699250.

Amyloidose

  • Siegismund CS, Escher F, Lassner D, Kühl U, Gross U, Fruhwald F, Wenzel P, Münzel T, Frey N, Linke RP, Schultheiss HP. Intramyocardial inflammation predicts adverse outcome in patients with cardiac AL amyloidosis. Eur J Heart Fail. 2018 Apr;20(4):751-757. doi: 10.1002/ejhf.1039. Epub 2017 Oct 25. PMID:
  • Lassner D, Rohde M, Gross UM, Escher F, Schultheiss HP, Linke RP, Kühl U. Classification of four chemically different amyloid types in routine endomyocardial biopsies by advanced immunohistochemistry. Amyloid. 2011 Jun;18 Suppl 1:76-8. doi: 10.3109/13506129.2011.574354027. Erratum in: Amyloid. 2011 Jun;18 Suppl 1:78. PMID: 21838439.

Perforin

  • Escher F, Kühl U, Lassner D, Stroux A, Gross U, Westermann D, Pieske B, Poller W, Schultheiss HP. High Perforin-Positive Cardiac Cell Infiltration and Male Sex Predict Adverse Long-Term Mortality in Patients With Inflammatory Cardiomyopathy. J Am Heart Assoc. 2017 Aug 18;6(8):e005352. doi: 10.1161/JAHA.116.005352. PMID: 28862949; PMCID: PMC5586411.

miRNA

  • Aleshcheva G, Pietsch H, Escher F, Schultheiss HP. MicroRNA profiling as a novel diagnostic tool for identification of patients with inflammatory and/or virally induced cardiomyopathies. ESC Heart Fail. 2020 Nov 20;8(1):408-22. doi: 10.1002/ehf2.13090.
  • Siegismund CS, Rohde M, Kühl U, Escher F, Schultheiss HP, Lassner D. Absent MicroRNAs in Different Tissues of Patients with Acquired Cardiomyopathy. Genomics Proteomics Bioinformatics. 2016 Aug;14(4):224-34. doi: 10.1016/j.gpb.2016.04.005. Epub 2016 Jul 28. PMID: 27475403; PMCID: PMC4996855.
  • Gast M, Schroen B, Voigt A, Haas J, Kuehl U, Lassner D, Skurk C, Escher F, Wang X, Kratzer A, Michalik K, Papageorgiou A, Peters T, Loebel M, Wilk S, Althof N, Prasanth KV, Katus H, Meder B, Nakagawa S, Scheibenbogen C, Schultheiss HP, Landmesser U, Dimmeler S, Heymans S, Poller W. Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity. J Mol Cell Biol. 2016 Apr;8(2):178-81. doi: 10.1093/jmcb/mjw003. Epub 2016 Jan 27. PMID: 26823496; PMCID: PMC6283121.
  • Kuehl U, Lassner D, Gast M, Stroux A, Rohde M, Siegismund C, Wang X, Escher F, Gross M, Skurk C, Tschoepe C, Loebel M, Scheibenbogen C, Schultheiss HP, Poller W. Differential Cardiac MicroRNA Expression Predicts the Clinical Course in Human Enterovirus Cardiomyopathy. Circ Heart Fail. 2015 May;8(3):605-18. doi: 10.1161/CIRCHEARTFAILURE.114.001475. Epub 2015 Mar 11. PMID: 25761932.
  • Kühl U, Rohde M, Lassner D, Gross UM, Escher F, Schultheiss HP. miRNA as activity markers in Parvo B19 associated heart disease. Herz. 2012 Sep;37(6):637-43. doi: 10.1007/s00059-012-3656-3. PMID: 22872003.

Biopsie

  • Schulz E, Jabs A, Gori T, Hink U, Sotiriou E, Tschöpe C, Schultheiss HP, Münzel T, Wenzel P. Feasibility and safety of left ventricular endomyocardial biopsy via transradial access: Technique and initial experience. Catheter Cardiovasc Interv. 2015 Oct;86(4):761-5. doi: 10.1002/ccd.25834. Epub 2015 Feb 3. PMID: 25586731.
  • Tschöpe C, Kherad B, Schultheiss HP. How to perform an endomyocardial biopsy? Turk Kardiyol Dern Ars. 2015 Sep;43(6):572-5. doi: 10.5543/tkda.2015.91298. PMID: 26363754.

SARS-CoV-2-Nachweis in den Herzmuskelbiopsien

  • Pietsch H, Escher F, Aleshcheva G, Baumeier C, Morawietz L, Elsaesser A, Schultheiss HP. Proof of SARS-CoV-2 Genomes in Endomyocardial Biopsy with Latency After Acute Infection. Int J Infect Dis. 2020 Oct 9:S1201-9712(20)32215-3. doi: 10.1016/j.ijid.2020.10.012. Epub ahead of print. PMID: 33045427; PMCID: PMC7546659.
  • Wenzel P, Kopp S, Göbel S, Jansen T, Geyer M, Hahn F, Kreitner KF, Escher F, Schultheiss HP, Münzel T. Evidence of SARS-CoV-2 mRNA in endomyocardial biopsies of patients with clinically suspected myocarditis tested negative for COVID-19 in nasopharyngeal swab. Cardiovasc Res. 2020 Aug 1;116(10):1661-1663. doi: 10.1093/cvr/cvaa160. PMID: 32562489; PMCID: PMC7337685.
  • Lindner D, Fitzek A, Bräuninger H, Aleshcheva G, Edler C, Meissner K, Scherschel K, Kirchhof P, Escher F, Schultheiss HP, Blankenberg S, Püschel K, Westermann D. Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases. JAMA Cardiol. 2020 Jul 27:e203551. doi: 10.1001/jamacardio.2020.3551. Epub ahead of print. PMID: 32730555; PMCID: PMC7385672.
  • Escher F, Pietsch H, Aleshcheva G, Bock T, Baumeier C, Elsaesser A, Wenzel P, Hamm C, Westenfeld R, Schultheiss M, Gross U, Morawietz L, Schultheiss HP. Detection of viral SARS-CoV-2 genomes and histopathological changes in endomyocardial biopsies. ESC Heart Fail. 2020 Jun 12;7(5):2440–7. doi: 10.1002/ehf2.12805. Epub ahead of print. PMID: 32529795; PMCID: PMC7307078.

Riesenzellmyokarditis

  • Escher F, Pietsch H, Aleshcheva G, Wenzel P, Fruhwald F, Stumpf C, Westermann D, Bauersachs J, Enseleit F, Ruschitzka F, Nägele H, Laugwitz KL, Haake H, Frey N, Brachmann J, Huber K, Braun-Dullaeus RC, Bergmann MW, Strotmann J, Grönefeld G, Krülls-Münch J, Westenfeld R, Skurk C, Landmesser U, Pieske B, Gross UM, Morawietz L, Schultheiss HP. Evaluation of Myocardial Gene Expression Profiling for Superior Diagnosis of Idiopathic Giant-Cell Myocarditis and Clinical Feasibility in a Large Cohort of Patients with Acute Cardiac Decompensation. J Clin Med. 2020 Aug 19;9(9):E2689. doi: 10.3390/jcm9092689. PMID: 32825201.
  • Lassner D, Siegismund CS, Kühl U, Rohde M, Stroux A, Escher F, Schultheiss HP. CCR5del32 genotype in human enteroviral cardiomyopathy leads to spontaneous virus clearance and improved outcome compared to wildtype CCR5. J Transl Med. 2018 Sep 4;16(1):249. doi: 10.1186/s12967-018-1610-8. PMID: 30180856; PMCID: PMC6123922.
  • Maleszewski JJ, Orellana VM, Hodge DO, Kuhl U, Schultheiss HP, Cooper LT. Long-term risk of recurrence, morbidity and mortality in giant cell myocarditis. Am J Cardiol. 2015 Jun 15;115(12):1733-8. doi: 10.1016/j.amjcard.2015.03.023. Epub 2015 Mar 24. PMID: 25882774.
  • Lassner D, Kühl U, Siegismund CS, Rohde M, Elezkurtaj S, Escher F, Tschöpe C, Gross UM, Poller W, Schultheiss HP. Improved diagnosis of idiopathic giant cell myocarditis and cardiac sarcoidosis by myocardial gene expression profiling. Eur Heart J. 2014 Aug 21;35(32):2186-95. doi: 10.1093/eurheartj/ehu101. Epub 2014 Mar 24. PMID: 24667923.
  • Lassner D, Kühl U, Rohde M, Siegismund CS, Schultheiss HP. CCR5del32 polymorphism is a protective factor in non-ischemic cardiomyopathy. Int J Cardiol. 2014 May 15;173(3):561-2. doi: 10.1016/j.ijcard.2014.03.123. Epub 2014 Mar 21. PMID: 24721485.
  • Elezkurtaj S, Lassner D, Schultheiss HP, Escher F. Vascular involvement in cardiac giant cell myocarditis: a new pathophysiological aspect. Clin Res Cardiol. 2014 Feb;103(2):161-3. doi: 10.1007/s00392-013-0638-2. Epub 2013 Nov 20. PMID: 24253072.

Therapie

  • Zobel T, Bock CT, Kühl U, Rohde M, Lassner D, Schultheiss HP, Schmidt-Lucke C. Telbivudine Reduces Parvovirus B19-Induced Apoptosis in Circulating Angiogenic Cells. Viruses. 2019 Mar 6;11(3):227. doi: 10.3390/v11030227. PMID: 30845701; PMCID: PMC6466312.
  • Poller W, Kaya Z, Muche M, Kasner M, Skurk C, Kappert K, Tauber R, Escher F, Schultheiss HP, Epple HJ, Landmesser U. High incidence of cardiac dysfunction and response to antiviral treatment in patients with chronic hepatitis C virus infection. Clin Res Cardiol. 2017 Jul;106(7):551-556. doi: 10.1007/s00392-017-1086-1. Epub 2017 Feb 24. PMID: 28236021.
  • Fruhwald F, Lassner D, Fruhwald S, Gross UM, Dapunt O, Schultheiss HP. Immunosuppressive treatment in fulminant myocarditis and gene expression pattern associated with, but no histological confirmation of giant cell myocarditis. ESC Heart Fail. 2017 May;4(2):190-192. doi: 10.1002/ehf2.12130. Epub 2017 Jan 31. PMID: 28451456; PMCID: PMC5396038.
  • Escher F, Kühl U, Lassner D, Poller W, Westermann D, Pieske B, Tschöpe C, Schultheiss HP. Long-term outcome of patients with virus-negative chronic myocarditis or inflammatory cardiomyopathy after immunosuppressive therapy. Clin Res Cardiol. 2016 Dec;105(12):1011-1020. doi: 10.1007/s00392-016-1011-z. Epub 2016 Jun 16. PMID: 27312326.
  • Schultheiss HP, Piper C, Sowade O, Waagstein F, Kapp JF, Wegscheider K, Groetzbach G, Pauschinger M, Escher F, Arbustini E, Siedentop H, Kuehl U. Betaferon in chronic viral cardiomyopathy (BICC) trial: Effects of interferon-β treatment in patients with chronic viral cardiomyopathy. Clin Res Cardiol. 2016 Sep;105(9):763-73. doi: 10.1007/s00392-016-0986-9. Epub 2016 Apr 25. PMID: 27112783.
  • Kühl U, Lassner D, von Schlippenbach J, Poller W, Schultheiss HP. Interferon-Beta improves survival in enterovirus-associated cardiomyopathy. J Am Coll Cardiol. 2012 Oct 2;60(14):1295-6. doi: 10.1016/j.jacc.2012.06.026. PMID: 23017536.
  • Schultheiss HP, Lassner D, Kühl U. Qualitätsanalysen der Therapie von Herzmuskelerkrankungen [Quality analysis for treatment of heart muscle diseases]. Dtsch Med Wochenschr. 2009 Oct;134 Suppl 6:S195-7. German. doi: 10.1055/s-0029-1241907. Epub 2009 Oct 15. PMID: 19834839.